Staff ML Research Scientist, Co-Folding and Affinity

Posted 2026-05-05
Remote, USA Full-time Immediate Start
    Job Description:
  • Drive the research and development of next-generation deep learning models for protein-ligand co-folding and affinity prediction
  • Bridge from research to commercial utility by equipping SandboxAQ’s software products with advanced predictive capabilities
  • Bring novel ideas and the content of scientific papers into the ideation, training, and benchmarking of complex models
  • Act as a technical beacon for the team, representing SandboxAQ scientifically and shaping its vision externally and internally
  • Mentor junior researchers and collaborate across engineering and product teams to foster a culture of technical rigor and rapid iteration
    Requirements:
  • PhD in Computer Science, Computational Chemistry, or a related field
  • At least 4 years of post-PhD experience, including experience in a professional industry setting
  • Direct, hands-on experience developing and executing leading-edge co-folding and/or affinity prediction models
  • Proven excellence in co-folding and/or affinity prediction, as demonstrated by participation in industrial projects and/or academic publications
  • Experience functioning within a professional software team, including proficiency in Python and modern ML frameworks (PyTorch/JAX) at scale
    Benefits:
  • Comprehensive medical, dental, and vision coverage for employees and dependents with generous employer premium contributions
  • Retirement savings with company matching
  • Paid parental leave
  • Inclusive family-building benefits
  • Flexible paid time off
  • Company-wide seasonal breaks
  • Support for flexible work arrangements that enable sustainable performance
  • Opportunities for continuous learning and growth through on-the-job development, cross-functional collaboration, and access to internal learning and development programs

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